A foreigner of international marriage increase in Korea. Due to cultural differences and linguistic problems, there is a lot of difficulties in communication. Marriage migrant women get stressed a stress in culture adjustment, and decreased the quality of life. The total sample was composed of 81 members of multicultural family. The results of hypothesis testings are as follows: Communication of multicultural family has significantly decrease stress in culture adjustment, and stress in culture adjustment has significantly decrease quality of life. But communication of multicultural family has significantly increase quality of life. Lastly, stress in culture adjustment mediates between communication of multicultural family and quality of life.